work Lung Cancer Longitudinal AI with Rule-Based Interpretability (CLARITY) Development of a foundational AI with Synthetic In Silico longitudinal Digital Humans. Virtual Lung Screening Trials (VLST) Virtual platform for evaluating imaging technologies AI in Lung Health Benchmarking Detection, Diagnostic, Segmentation and Radiomics-based analysis Reality Check, In Silico COVID-19 Imaging Case-study (ReviCOVID) Virtual Imaging Trials Improved the Transparency and Reliability of AI Systems I-Predict Weakly Supervised Classification fun